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Endothelial cell senescence with aging in healthy humans: prevention by habitual exercise and relation to vascular endothelial function

Cellular senescence is emerging as a key mechanism of age-related vascular endothelial dysfunction, but evidence in healthy humans is lacking. Moreover, the influence of lifestyle factors such as habitual exercise on endothelial cell (EC) senescence is unknown. We tested the hypothesis that EC senes...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Rossman, Matthew J., Kaplon, Rachelle E., Hill, Sierra D., McNamara, Molly N., Santos-Parker, Jessica R., Pierce, Gary L., Seals, Douglas R., Donato, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792201/
https://ncbi.nlm.nih.gov/pubmed/28971843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00416.2017
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