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How does pressure overload cause cardiac hypertrophy and dysfunction? High-ouabain affinity cardiac Na(+) pumps are crucial
Left ventricular hypertrophy is frequently observed in hypertensive patients and is believed to be due to the pressure overload and cardiomyocyte stretch. Three recent reports on mice with genetically engineered Na(+) pumps, however, have demonstrated that cardiac ouabain-sensitive α(2)-Na(+) pumps...
में बचाया:
| में प्रकाशित: | Am J Physiol Heart Circ Physiol |
|---|---|
| मुख्य लेखक: | |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Physiological Society
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5792198/ https://ncbi.nlm.nih.gov/pubmed/28733446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00131.2017 |
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