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Central effects of insulin detemir on feeding, body weight, and metabolism in rats

Insulin detemir (DET) is a basal insulin analog that, in contrast to other long-acting forms of insulin, has significant weight-gain-sparing effects in diabetic patients. We hypothesized that this effect of DET may be due to its enhanced catabolic action in the central nervous system. We investigate...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Vasselli, Joseph R., Pi-Sunyer, F. Xavier, Wall, Daniel G., John, Catherine S., Chapman, Colin D., Currie, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792141/
https://ncbi.nlm.nih.gov/pubmed/28720583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00111.2016
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