Insulin detemir attenuates food intake, body weight gain and fat mass gain in diet-induced obese Sprague–Dawley rats

OBJECTIVE: Initiation and intensification of insulin therapy commonly causes weight gain, a barrier to therapy. A contrasting body of evidence indicates that insulin functions as an adiposity negative feedback signal and reduces food intake, weight gain and adiposity via action in the central nervou...

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Bibliographic Details
Main Authors: Rojas, J M, Printz, R L, Niswender, K D
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302138/
https://ncbi.nlm.nih.gov/pubmed/23449422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nutd.2011.6
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