Stereoselective differences between the reinforcing and motivational effects of cathinone-derived 4-methylmethcathinone (mephedrone) in self-administering rats

Mephedrone (4-methylmethcathinone (4-MMC)) (MEPH) is a new psychoactive substance (NPS) of the synthetic cathinone class. MEPH has a chiral center and exists as two enantiomers (R-,S-MEPH), yet stereospecific effects of MEPH have not been extensively investigated in preclinical assays. Because signi...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Philogene-Khalid, Helene L., Simmons, Steven J., Nayak, Sunil, Martorana, Rose M., Su, Shu H., Caro, Yohanka, Ranieri, Brona, DiFurio, Kathryn, Mo, Lili, Gentile, Taylor A., Murad, Ali, Reitz, Allen B., Muschamp, John W., Rawls, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792057/
https://ncbi.nlm.nih.gov/pubmed/28885007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00212
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