Synthetic cathinones and stereochemistry: S enantiomer of mephedrone reduces anxiety- and depressant-like effects in cocaine- or MDPV-abstinent rats()

BACKGROUND AND PURPOSE: The neuropharmacological profile of the synthetic cathinone mephedrone (MEPH) is influenced by stereochemistry. Both MEPH enantiomers are monoamine transporter substrates, but R-MEPH is primarily responsible for rewarding effects of MEPH as it produces greater locomotor activ...

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Detalhes bibliográficos
Publicado no:Drug Alcohol Depend
Main Authors: Philogene-Khalid, Helene L., Hicks, Callum, Reitz, Allen B., Liu-Chen, Lee-Yuan, Rawls, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548612/
https://ncbi.nlm.nih.gov/pubmed/28646714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2017.04.024
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