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IFNγ inhibits G-CSF induced neutrophil expansion and invasion of the CNS to prevent viral encephalitis

Emergency hematopoiesis facilitates the rapid expansion of inflammatory immune cells in response to infections by pathogens, a process that must be carefully regulated to prevent potentially life threatening inflammatory responses. Here, we describe a novel regulatory role for the cytokine IFNγ that...

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Библиографические подробности
Опубликовано в: :PLoS Pathog
Главные авторы: Ramakrishna, Chandran, Cantin, Edouard M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792029/
https://ncbi.nlm.nih.gov/pubmed/29352287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006822
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