COBRA methods and metabolic drug targets in cancer

The identification of therapeutic strategies exploiting the metabolic alterations of malignant cells is a relevant area in cancer research. Here, we discuss a novel computational method, based on the COBRA (COnstraint-Based Reconstruction and Analysis) framework for metabolic networks, to perform th...

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Bibliographic Details
Published in:Mol Cell Oncol
Main Authors: Apaolaza, Iñigo, José-Eneriz, Edurne San, Agirre, Xabier, Prósper, Felipe, Planes, Francisco J.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791858/
https://ncbi.nlm.nih.gov/pubmed/29404389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1389672
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