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Intratumoral bacteria may elicit chemoresistance by metabolizing anticancer agents
We recently reported that bacteria can be found within pancreatic ductal adenocarcinoma (PDAC) tumors. Some of these bacteria can metabolize and thereby inactivate the nucleoside analog gemcitabine. We demonstrated that the long isoform of the bacterial enzyme cytidine deaminase (CDD) mediates the m...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5791857/ https://ncbi.nlm.nih.gov/pubmed/29404397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1405139 |
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