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Intratumoral bacteria may elicit chemoresistance by metabolizing anticancer agents
We recently reported that bacteria can be found within pancreatic ductal adenocarcinoma (PDAC) tumors. Some of these bacteria can metabolize and thereby inactivate the nucleoside analog gemcitabine. We demonstrated that the long isoform of the bacterial enzyme cytidine deaminase (CDD) mediates the m...
Guardat en:
| Publicat a: | Mol Cell Oncol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5791857/ https://ncbi.nlm.nih.gov/pubmed/29404397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1405139 |
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