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Epigenetic inactivation of arginine biosynthesis genes in paediatric intracranial ependymoma

Aberrant cellular metabolism is recognized as a major event in the growth and development of many cancers and the targetting of metabolic defects in tumour cells represents a new therapeutic opportunity. For example, cells that do not express sufficient levels of argininosuccinate synthetase-1 (ASS1...

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Uloženo v:
Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Karakoula, Katherine, Syed, Nelofer, Jacques, Thomas, Phipps, Kim, Thompson, Dominic, Darling, John, Warr, Tracy
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791677/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox238.044
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