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Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry

To build comprehensive models of cellular states and interactions in normal and diseased tissue, genetic and proteomic information must be extracted with single-cell and spatial resolution. Here, we extended imaging mass cytometry to enable multiplexed detection of mRNA and proteins in tissues. Thre...

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Publicat a:Cell Syst
Autors principals: Schulz, Daniel, Zanotelli, Vito Riccardo Tomaso, Fischer, Jana Raja, Schapiro, Denis, Engler, Stefanie, Lun, Xiao-Kang, Jackson, Hartland Warren, Bodenmiller, Bernd
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791659/
https://ncbi.nlm.nih.gov/pubmed/29289569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.12.001
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