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Role of mGlu(5) Receptors and Inhibitory Neurotransmission in M(1) Dependent Muscarinic LTD in the Prefrontal Cortex: Implications in Schizophrenia

Selective potentiation of the mGlu(5) subtype of metabotropic glutamate (mGlu) receptor using positive allosteric modulators (PAMs) has robust cognition-enhancing effects in rodent models that are relevant for schizophrenia. Until recently, these effects were thought to be due to potentiation of mGl...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:ACS Chem Neurosci
Κύριοι συγγραφείς: Ghoshal, Ayan, Moran, Sean P., Dickerson, Jonathan W., Joffe, Max E., Grueter, Brad A., Xiang, Zixiu, Lindsley, Craig W., Rook, Jerri M., Conn, P. Jeffrey
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791524/
https://ncbi.nlm.nih.gov/pubmed/28679049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00167
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