Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model

BACKGROUND: Surgical resection is a universal component of glioma therapy. Little is known about the postoperative microenvironment due to limited preclinical models. Thus, we sought to develop a glioma resection and recurrence model in syngeneic immune-competent mice to understand how surgical rese...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Okolie, Onyinyechukwu, Bago, Juli R., Schmid, Ralf S., Irvin, David M., Bash, Ryan E., Miller, C. Ryan, Hingtgen, Shawn D.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Basic and Translational Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791515/
https://ncbi.nlm.nih.gov/pubmed/27298311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now117
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