Age-related cognitive impairment is associated with long-term neuroinflammation and oxidative stress in a mouse model of episodic systemic inflammation

BACKGROUND: Microglia function is essential to maintain the brain homeostasis. Evidence shows that aged microglia are primed and show exaggerated response to acute inflammatory challenge. Systemic inflammation signals to the brain inducing changes that impact cognitive function. However, the mechani...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Neuroinflammation
Päätekijät: d’Avila, Joana Costa, Siqueira, Luciana Domett, Mazeraud, Aurélien, Azevedo, Estefania Pereira, Foguel, Debora, Castro-Faria-Neto, Hugo Caire, Sharshar, Tarek, Chrétien, Fabrice, Bozza, Fernando Augusto
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2018
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791311/
https://ncbi.nlm.nih.gov/pubmed/29382344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1059-y
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia