Glut9-mediated Urate Uptake Is Responsible for Its Protective Effects on Dopaminergic Neurons in Parkinson’s Disease Models

Considerable evidence has shown that elevated plasma or cerebrospinal fluid (CSF) urate levels correlated with a reduced risk of Parkinson’s disease (PD). Based on its anti-oxidative properties, urate might serve as one of promising neuroprotective candidates for PD. However, how urate is transporte...

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Udgivet i:Front Mol Neurosci
Main Authors: Bi, Mingxia, Jiao, Qian, Du, Xixun, Jiang, Hong
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790811/
https://ncbi.nlm.nih.gov/pubmed/29434538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00021
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