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Separation of atropisomers by chiral liquid chromatography and thermodynamic analysis of separation mechanism()

In the pharmaceutical industry, the analysis of atropisomers is of considerable interest from a scientific and regulatory perspective. The compound of interest contains two stereogenic axes due to the hindered rotation around the single bonds connecting the aryl groups, which results in four potenti...

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Podrobná bibliografie
Vydáno v:J Pharm Anal
Hlavní autoři: Zhang, Ling, Hu, Yue, Galella, Elizabeth, Tomasella, Frank P., Fish, William P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Xi'an Jiaotong University 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790684/
https://ncbi.nlm.nih.gov/pubmed/29404032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2017.03.003
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