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Separation of atropisomers by chiral liquid chromatography and thermodynamic analysis of separation mechanism()
In the pharmaceutical industry, the analysis of atropisomers is of considerable interest from a scientific and regulatory perspective. The compound of interest contains two stereogenic axes due to the hindered rotation around the single bonds connecting the aryl groups, which results in four potenti...
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| Publicado no: | J Pharm Anal |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Xi'an Jiaotong University
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5790684/ https://ncbi.nlm.nih.gov/pubmed/29404032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2017.03.003 |
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