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Penalized Nonlinear Mixed Effects Model to Identify Biomarkers that Predict Disease Progression
Precise modeling of disease progression in neurodegenerative disorders may enable early intervention before clinical manifestation of a disease, which is crucial since early intervention at the premanifest stage is expected to be more effective. Neuroimaging biomarkers are indicative of the underlyi...
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| Veröffentlicht in: | Biometrics |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5790569/ https://ncbi.nlm.nih.gov/pubmed/28182831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12663 |
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