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Penalized Nonlinear Mixed Effects Model to Identify Biomarkers that Predict Disease Progression

Precise modeling of disease progression in neurodegenerative disorders may enable early intervention before clinical manifestation of a disease, which is crucial since early intervention at the premanifest stage is expected to be more effective. Neuroimaging biomarkers are indicative of the underlyi...

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Bibliografische gegevens
Gepubliceerd in:Biometrics
Hoofdauteurs: Chen, Huaihou, Zeng, Donglin, Wang, Yuanjia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790569/
https://ncbi.nlm.nih.gov/pubmed/28182831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12663
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