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Oxidative stress promotes exit from the stem cell state and spontaneous neuronal differentiation

Reactive oxygen species (ROS) play important roles in fundamental cellular processes such as proliferation and survival. Here we investigated the effect of oxidative stress on stem cell maintenance and neuronal differentiation in a human embryonic stem cell (hESC) model, Ntera2 (NT2). CM-H2DCFDA and...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Hu, Qidong, Khanna, Puja, Ee Wong, Belinda Shu, Lin Heng, Zealyn Shi, Subhramanyam, Charannya Sozheesvari, Thanga, Lal Zo, Sing Tan, Sharon Wui, Baeg, Gyeong Hun
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790534/
https://ncbi.nlm.nih.gov/pubmed/29423117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23786
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