Phosphatase of regenerating liver-3 is expressed in acute lymphoblastic leukemia and mediates leukemic cell adhesion, migration and drug resistance

Phosphatase of regenerating liver-3 (PRL-3/PTP4A3) is upregulated in multiple cancers, including BCR-ABL1- and ETV6-RUNX-positive acute lymphoblastic leukemia (ALL). With this study, we aim to characterize the biological role of PRL-3 in B cell ALL (B-ALL). Here, we demonstrate that PRL-3 expression...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hjort, Magnus A., Abdollahi, Pegah, Vandsemb, Esten N., Fenstad, Mona H., Lund, Bendik, Slørdahl, Tobias S., Børset, Magne, Rø, Torstein B.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790482/
https://ncbi.nlm.nih.gov/pubmed/29423065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23186
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