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Schisandrol B and schisandrin B inhibit TGFβ1-mediated NF-κB activation via a Smad-independent mechanism

Aberrant transforming growth factor β1 (TGFβ1) signaling plays a pathogenic role in the development of vascular fibrosis. We have reported that Schisandra chinensis fruit extract (SCE), which has been used as a traditional oriental medicine, suppresses TGFβ1-mediated phenotypes in vascular smooth mu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chun, Jung Nyeo, Park, Soonbum, Lee, Sanghoon, Kim, Jae-Kyung, Park, Eun-Jung, Kang, MinJi, Kim, Hye Kyung, Park, Jong Kwan, So, Insuk, Jeon, Ju-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790451/
https://ncbi.nlm.nih.gov/pubmed/29423034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23213
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