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Micro-RNA149 confers taxane resistance to malignant mesothelioma cells via regulation of P-glycoprotein expression

Multidrug resistance (MDR) represents a major hindrance to the efficacy of cancer chemotherapeutics. While surgical resection, radiation, and chemotherapy can be used to reduce tumor size, the subsequent appearance of drug resistant cells is a frequent problem. One of the main contributors to the de...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Kenworthy, Rachael, Bosco, Dale B., DeLigio, James T., Zorio, Diego A. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790384/
https://ncbi.nlm.nih.gov/pubmed/29261027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1415677
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