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Human Mesenchymal Stem Cells Are Resistant to Paclitaxel by Adopting a Non-Proliferative Fibroblastic State

Human mesenchymal stem cell (hMSC) resistance to the apoptotic effects of chemotherapeutic drugs has been of major interest, as these cells can confer this resistance to tumor microenvironments. However, the effects of internalized chemotherapeutics upon hMSCs remain largely unexplored. In this stud...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bosco, Dale B., Kenworthy, Rachael, Zorio, Diego A. R., Sang, Qing-Xiang Amy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452335/
https://ncbi.nlm.nih.gov/pubmed/26029917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128511
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