DNA hypermethylation as a predictor of extramural vascular invasion (EMVI) in rectal cancer

Purpose: DNA hypermethylation in gene promoter regions (CpG islands) is emerging as an important pathway in colorectal cancer tumourigenesis. Whilst genetic mutations have been associated with extramural vascular invasion (EMVI) in rectal cancer, no such association has yet been made with epigenetic...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Kokelaar, Rory F., Jones, Huw G., Williamson, Jeremy, Williams, Namor, Griffiths, A. Paul, Beynon, John, Jenkins, Gareth J., Harris, Dean A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790361/
https://ncbi.nlm.nih.gov/pubmed/29260978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1416933
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