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Review of the development of DNA methylation as a marker of response to neoadjuvant therapy and outcomes in rectal cancer

There is much debate around the preoperative treatment of colorectal cancer and, in particular, neoadjuvant chemoradiotherapy in locally advanced rectal cancer. This treatment carries a significant risk of harmful side effects and has a highly variable response rate. Predictive biomarkers have been...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Williamson, Jeremy S., Harris, Dean A., Beynon, John, Jenkins, Gareth J.S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511540/
https://ncbi.nlm.nih.gov/pubmed/26203306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0111-3
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