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The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in hepatocyte-specific TAK1-deleted mice

Hepatocyte death is associated with liver inflammation, fibrosis and hepatocellular carcinoma (HCC). Damaged cells trigger inflammation through activation of Toll-like receptors (TLRs). Although the role of TLR4 in HCC development has been reported, the role of TLR9 in the development of HCC remains...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Cancer
Hauptverfasser: Song, Isabelle Jingyi, Yang, Yoon Mee, Inokuchi-Shimizu, Sayaka, Roh, Yoon Seok, Yang, Ling, Seki, Ekihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790193/
https://ncbi.nlm.nih.gov/pubmed/28875549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31029
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