Natural polyreactive IgA antibodies coat the intestinal microbiota

Large quantities of immunoglobulin A (IgA) are constitutively secreted by intestinal plasma cells to coat and contain the commensal microbiota, yet the specificity of these antibodies remains elusive. Here, we profiled the reactivities of single murine IgA plasma cells by cloning and characterizing...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Bunker, Jeffrey J., Erickson, Steven A., Flynn, Theodore M., Henry, Carole, Koval, Jason C., Meisel, Marlies, Jabri, Bana, Antonopoulos, Dionysios A., Wilson, Patrick C., Bendelac, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790183/
https://ncbi.nlm.nih.gov/pubmed/28971969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan6619
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