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Hedgehog pathway drives fusion-negative rhabdomyosarcoma initiated from non-myogenic endothelial progenitors

Rhabdomyosarcoma (RMS) is a pediatric soft tissue sarcoma that histologically resembles embryonic skeletal muscle. RMS occurs throughout the body and an exclusively myogenic origin does not account for RMS occurring in sites devoid of skeletal muscle. We previously described a RMS model activating a...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Drummond, Catherine J., Hanna, Jason A., Garcia, Matthew R., Devine, Daniel J., Heyrana, Alana J., Finkelstein, David, Rehg, Jerold E., Hatley, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790179/
https://ncbi.nlm.nih.gov/pubmed/29316425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.12.001
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