PAX7 is a required target for microRNA-206-induced differentiation of fusion-negative rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood. RMS can be parsed based on clinical outcome into two subtypes, fusion-positive RMS (FP-RMS) or fusion-negative RMS (FN-RMS) based on the presence or absence of either PAX3-FOXO1 or PAX7-FOXO1 gene fusions. In both RMS subtyp...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Hanna, J A, Garcia, M R, Go, J C, Finkelstein, D, Kodali, K, Pagala, V, Wang, X, Peng, J, Hatley, M E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143388/
https://ncbi.nlm.nih.gov/pubmed/27277678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.159
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