Fenofibrate prevents skeletal muscle loss in mice with lung cancer

The cancer anorexia cachexia syndrome is a systemic metabolic disorder characterized by the catabolism of stored nutrients in skeletal muscle and adipose tissue that is particularly prevalent in nonsmall cell lung cancer (NSCLC). Loss of skeletal muscle results in functional impairments and increase...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Goncalves, Marcus D., Hwang, Seo-Kyoung, Pauli, Chantal, Murphy, Charles J., Cheng, Zhe, Hopkins, Benjamin D., Wu, David, Loughran, Ryan M., Emerling, Brooke M., Zhang, Guoan, Fearon, Douglas T., Cantley, Lewis C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789923/
https://ncbi.nlm.nih.gov/pubmed/29311302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714703115
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