Fenofibrate prevents skeletal muscle loss in mice with lung cancer

The cancer anorexia cachexia syndrome is a systemic metabolic disorder characterized by the catabolism of stored nutrients in skeletal muscle and adipose tissue that is particularly prevalent in nonsmall cell lung cancer (NSCLC). Loss of skeletal muscle results in functional impairments and increase...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Goncalves, Marcus D., Hwang, Seo-Kyoung, Pauli, Chantal, Murphy, Charles J., Cheng, Zhe, Hopkins, Benjamin D., Wu, David, Loughran, Ryan M., Emerling, Brooke M., Zhang, Guoan, Fearon, Douglas T., Cantley, Lewis C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789923/
https://ncbi.nlm.nih.gov/pubmed/29311302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714703115
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