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Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer

Cancer cells can adapt to nutrient poor conditions by rewiring their metabolism and using alternate fuel sources. Identifying these adaptive metabolic pathways may provide novel targets for cancer therapy. Here, we identify a subset of non-small cell lung cancer (NSCLC) cell lines that survive in th...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Hodakoski, Cindy, Hopkins, Benjamin D., Zhang, Guoan, Su, Taojunfeng, Cheng, Zhe, Morris, Roxanne, Rhee, Kyu Y., Goncalves, Marcus D., Cantley, Lewis C.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356657/
https://ncbi.nlm.nih.gov/pubmed/30609754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010037
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