Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity

The arthropod-transmitted chikungunya virus (CHIKV) causes a flu-like disease that is characterized by incapacitating arthralgia. The re-emergence of CHIKV and the continual risk of new epidemics have reignited research in CHIKV pathogenesis. Virus-specific antibodies have been shown to control viru...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Lum, Fok-Moon, Couderc, Thérèse, Chia, Bing-Shao, Ong, Ruo-Yan, Her, Zhisheng, Chow, Angela, Leo, Yee-Sin, Kam, Yiu-Wing, Rénia, Laurent, Lecuit, Marc, Ng, Lisa F. P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789897/
https://ncbi.nlm.nih.gov/pubmed/29382880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20305-4
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