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Cardiogenic programming of human pluripotent stem cells by dose-controlled activation of EOMES
Master cell fate determinants are thought to induce specific cell lineages in gastrulation by orchestrating entire gene programs. The T-box transcription factor EOMES (eomesodermin) is crucially required for the development of the heart—yet it is equally important for endoderm specification suggesti...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5789885/ https://ncbi.nlm.nih.gov/pubmed/29382828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02812-6 |
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