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Nucleophilic fluoroalkylation/cyclization route to fluorinated phthalides
Discribed in this article is a versatile and practical method for the synthesis of C3-perfluoroalkyl-substituted phthalides in a one-pot manner. Upon treatment of KF or triethylamine, 2-cyanobenzaldehyde reacted with (perfluoroalkyl)trimethylsilanes via nucleophilic addition and subsequent intramole...
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| Gepubliceerd in: | Beilstein J Org Chem |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Beilstein-Institut
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5789380/ https://ncbi.nlm.nih.gov/pubmed/29441140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.12 |
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