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Selenoprotein K Increases Efficiency of DHHC6 Catalyzed Protein Palmitoylation by Stabilizing the Acyl-DHHC6 Intermediate

Selenoprotein K (SELENOK) is a selenocysteine (Sec)-containing protein localized in the endoplasmic reticulum (ER) membrane where it interacts with the DHHC6 (where single letter symbols represent Asp-His-His-Cys amino acids) enzyme to promote protein acyl transferase (PAT) reactions. PAT reactions...

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Bibliographic Details
Published in:Antioxidants (Basel)
Main Authors: Fredericks, Gregory J., Hoffmann, FuKun W., Hondal, Robert J., Rozovsky, Sharon, Urschitz, Johann, Hoffmann, Peter R.
Format: Artigo
Language:Inglês
Published: MDPI 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789314/
https://ncbi.nlm.nih.gov/pubmed/29286308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox7010004
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