Mechanisms driving the antibacterial and antibiofilm properties of Hp1404 and its analogue peptides against multidrug-resistant Pseudomonas aeruginosa

Hp1404, identified from the venom of the scorpion Heterometrus petersii, displays antimicrobial activity with cytotoxicity. Several synthetic peptides were designed based on the parent peptide Hp1404 to reduce cytotoxicity and improve activity (deletion of glycine and phenylalanine, substitution wit...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Kim, Min Kyung, Kang, Hee Kyoung, Ko, Su Jin, Hong, Min Ji, Bang, Jeong Kyu, Seo, Chang Ho, Park, Yoonkyung
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789083/
https://ncbi.nlm.nih.gov/pubmed/29379033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19434-7
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