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Mechanisms driving the antibacterial and antibiofilm properties of Hp1404 and its analogue peptides against multidrug-resistant Pseudomonas aeruginosa

Hp1404, identified from the venom of the scorpion Heterometrus petersii, displays antimicrobial activity with cytotoxicity. Several synthetic peptides were designed based on the parent peptide Hp1404 to reduce cytotoxicity and improve activity (deletion of glycine and phenylalanine, substitution wit...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Kim, Min Kyung, Kang, Hee Kyoung, Ko, Su Jin, Hong, Min Ji, Bang, Jeong Kyu, Seo, Chang Ho, Park, Yoonkyung
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789083/
https://ncbi.nlm.nih.gov/pubmed/29379033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19434-7
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