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Chemotherapy drugs cyclophosphamide, cisplatin and doxorubicin induce germ cell loss in an in vitro model of the prepubertal testis

Long term survival rates for childhood cancers is steadily increasing, however cancer survivors can experience fertility problems as a consequence of chemotherapy treatment. This is particularly problematic for young boys, for whom no fertility preservation treatment is yet established. Here, we hav...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Smart, Ellie, Lopes, Federica, Rice, Siobhan, Nagy, Boglarka, Anderson, Richard A., Mitchell, Rod T., Spears, Norah
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788858/
https://ncbi.nlm.nih.gov/pubmed/29379115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19761-9
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