Mechanical loading disrupts osteocyte plasma membranes which initiates mechanosensation events in bone

Osteocytes sense loading in bone, but their mechanosensation mechanisms remain poorly understood. Plasma membrane disruptions (PMD) develop with loading under physiological conditions in many cell types (e.g., myocytes, endothelial cells). These PMD foster molecular flux across cell membranes that p...

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Pubblicato in:J Orthop Res
Autori principali: Yu, Kanglun, Sellman, David P., Bahraini, Anoosh, Hagan, Mackenzie L., Elsherbini, Ahmed, Vanpelt, Kayce T., Marshall, Peyton L., Hamrick, Mark W., McNeil, Anna, McNeil, Paul L., McGee-Lawrence, Meghan E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788741/
https://ncbi.nlm.nih.gov/pubmed/28755471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23665
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