Experimental evidence of good efficacy and reduced toxicity with peptide-doxorubicin to treat gastric cancer

BACKGROUND: To compare the efficacy and toxicity of peptide-doxorubicin (PDOX) and doxorubicin (DOX) on nude mice models of human gastric cancer. RESULTS: Both PDOX and DOX could significantly inhibit tumor growth compared with Control (P < 0.05) in both subcutaneous and orthotopic models. Animal...

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Publicado en:Oncotarget
Autores principales: Zhang, Jue, Yuan, Jing-Ping, Wang, Qun, Shao, Li-Hua, Liu, Shao-Ping, Firestone, Raymond A., Hong, Ya-Ping, Li, Ji-Guo, Xin, Yan-Chao, Li, Yan
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788612/
https://ncbi.nlm.nih.gov/pubmed/29416744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23319
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