The intracellular microbial sensor NLRP4 directs Rho-actin signaling to facilitate Group A Streptococcus-containing autophagosome-like vacuole formation

Xenophagy, also known as antibacterial autophagy, functions as a crucial defense system that can utilize intracellular pattern recognition sensors, such as NLRP4, to recognize and selectively eliminate bacterial pathogens. However, little is known about how NLRP4 regulates xenophagy. Here, we report...

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Detalles Bibliográficos
Publicado en:Autophagy
Autores principales: Nozawa, Takashi, Aikawa, Chihiro, Minowa-Nozawa, Atsuko, Nakagawa, Ichiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2017
Materias:
Basic Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788493/
https://ncbi.nlm.nih.gov/pubmed/29099277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1358343
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