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Exploring the role of CENP-A Ser18 phosphorylation in CIN and Tumorigenesis
Chromosome instability (CIN) contributes to the development of many cancer. In this paper, we summarize our recent finding that a novel pathway by which FBW7 loss promotes Centromere Protein A (CENP-A) phosphorylation on Serine 18 through Cyclin E1/CDK2, therefore promoting CIN and tumorigenesis. Ou...
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| Vydáno v: | Cell Cycle |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5788445/ https://ncbi.nlm.nih.gov/pubmed/28980868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1387698 |
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