Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies

Next-generation sequencing (NGS)–based targeted gene capture panels are used to profile hematopoietic malignancies to guide prognostication and treatment decisions. Because these panels include genes associated with hereditary hematopoietic malignancies (HHMs), we hypothesized that these panels coul...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Drazer, Michael W., Kadri, Sabah, Sukhanova, Madina, Patil, Sushant A., West, Allison H., Feurstein, Simone, Calderon, Dalein A., Jones, Matthew F., Weipert, Caroline M., Daugherty, Christopher K., Ceballos-López, Adrián A., Raca, Gordana, Lingen, Mark W., Li, Zejuan, Segal, Jeremy P., Churpek, Jane E., Godley, Lucy A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787862/
https://ncbi.nlm.nih.gov/pubmed/29365323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017013037
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