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Glutaminolysis is required for transforming growth factor-β1–induced myofibroblast differentiation and activation

Myofibroblasts participate in physiological wound healing and pathological fibrosis. Myofibroblast differentiation is characterized by the expression of α-smooth muscle actin and extracellular matrix proteins and is dependent on metabolic reprogramming. In this study, we explored the role of glutami...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Bernard, Karen, Logsdon, Naomi J., Benavides, Gloria A., Sanders, Yan, Zhang, Jianhua, Darley-Usmar, Victor M., Thannickal, Victor J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787800/
https://ncbi.nlm.nih.gov/pubmed/29222329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000444
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