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Progesterone receptor A promotes invasiveness and metastasis of luminal breast cancer by suppressing regulation of critical microRNAs by estrogen

Distal metastasis of luminal breast cancer is frequent and incurable, yet the metastasis mechanisms are poorly understood. Estrogen, even at postmenopausal concentrations, suppresses invasiveness of luminal breast cancer cells through the estrogen receptor (ER). Invasive tumors overexpress the short...

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書目詳細資料
發表在:J Biol Chem
Main Authors: McFall, Thomas, McKnight, Brooke, Rosati, Rayna, Kim, Seongho, Huang, Yanfang, Viola-Villegas, Nerissa, Ratnam, Manohar
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787796/
https://ncbi.nlm.nih.gov/pubmed/29162724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.812438
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