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Progesterone receptor A promotes invasiveness and metastasis of luminal breast cancer by suppressing regulation of critical microRNAs by estrogen

Distal metastasis of luminal breast cancer is frequent and incurable, yet the metastasis mechanisms are poorly understood. Estrogen, even at postmenopausal concentrations, suppresses invasiveness of luminal breast cancer cells through the estrogen receptor (ER). Invasive tumors overexpress the short...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: McFall, Thomas, McKnight, Brooke, Rosati, Rayna, Kim, Seongho, Huang, Yanfang, Viola-Villegas, Nerissa, Ratnam, Manohar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787796/
https://ncbi.nlm.nih.gov/pubmed/29162724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.812438
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