Progesterone receptor A promotes invasiveness and metastasis of luminal breast cancer by suppressing regulation of critical microRNAs by estrogen

Distal metastasis of luminal breast cancer is frequent and incurable, yet the metastasis mechanisms are poorly understood. Estrogen, even at postmenopausal concentrations, suppresses invasiveness of luminal breast cancer cells through the estrogen receptor (ER). Invasive tumors overexpress the short...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: McFall, Thomas, McKnight, Brooke, Rosati, Rayna, Kim, Seongho, Huang, Yanfang, Viola-Villegas, Nerissa, Ratnam, Manohar
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2018
Aiheet:
Molecular Bases of Disease
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787796/
https://ncbi.nlm.nih.gov/pubmed/29162724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.812438
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