Induction of Short NFATc1/αA Isoform Interferes with Peripheral B Cell Differentiation

In lymphocytes, immune receptor signals induce the rapid nuclear translocation of preformed cytosolic NFAT proteins. Along with co-stimulatory signals, persistent immune receptor signals lead to high levels of NFATc1/αA, a short NFATc1 isoform, in effector lymphocytes. Whereas NFATc1 is not expresse...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Muhammad, Khalid, Rudolf, Ronald, Pham, Duong Anh Thuy, Klein-Hessling, Stefan, Takata, Katsuyoshi, Matsushita, Nobuko, Ellenrieder, Volker, Kondo, Eisaku,  Serfling, Edgar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787671/
https://ncbi.nlm.nih.gov/pubmed/29416540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00032
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